Reference SummaryHeston WE, 1963;():247-68

Title

 Genetics of Neoplasia

Authors

 Heston WE

Journal

Volume

Issue

Year

 1963

Pages

 247-68

Abstract

Links

 J:23470 – MGI References

Strain Notes

Strain Note
BALB/c Mice were NOT carriers of infectious MMTV.

Models
Strain Model Name Treatment Agent(s) Organ Affected Frequency Model Details
NH Adrenal gland - Cortex adenoma Adrenal gland - Cortex

high
NH Adrenal gland - Cortex carcinoma
  • castration
 Adrenal gland - Cortex

high
CE Adrenal gland - Cortex tumor
  • castration
 Adrenal gland - Cortex

high
BALB/c Blood vessel hemangioendothelioma
  • o-aminoazotoluene
 Blood vessel

high
HR Hrhr Blood vessel hemangioendothelioma
  • 4-o-tolylazo-o-toluidine (2-amino-5-azotoluene)
 Blood vessel

54.0 - 76.0
C3H Eye - Harderian gland tumor Eye - Harderian gland

observed
C57L Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

25
C58 Leukocyte leukemia Leukocyte

high
AKR Leukocyte leukemia Leukocyte

high
C3Hf Liver hepatoma
  • diethylstilbestrol (DES)
 Liver

72
C3H Liver hepatoma Liver

85
C3HeB Liver hepatoma Liver

30 - 91
A Lung tumor Lung

90
SWR Lung tumor Lung

80
BALB/c Lung tumor Lung

26 - 29
BL Lung tumor Lung

26
C3H Mammary gland tumor
  • MMTV - mouse mammary tumor virus
 Mammary gland

100
A Mammary gland tumor Mammary gland

low - high
DBA Mammary gland tumor Mammary gland

high
RIII Mammary gland tumor Mammary gland

high
BALB/c Mammary gland tumor Mammary gland

low
BALB/c Mammary gland tumor
  • MMTV - mouse mammary tumor virus
 Mammary gland

high
CC57BR Mammary gland tumor Mammary gland

0
CC57BR Mammary gland tumor
  • MMTV - mouse mammary tumor virus
 Mammary gland

55
CC57W Mammary gland tumor Mammary gland

0
CC57W Mammary gland tumor
  • MMTV - mouse mammary tumor virus
 Mammary gland

55
CBA Mesodermal cell/mesoblast sarcoma
  • methylcholanthrene (MCA)
 Mesodermal cell/mesoblast

high
A Myoepithelial cell myoepithelioma Myoepithelial cell

observed
BALB/c Myoepithelial cell myoepithelioma Myoepithelial cell

observed
C3HeB Ovary tumor Ovary

29 - 47
C57BL Pituitary gland adenoma
  • estrogen
 Pituitary gland

very high
HR Hrhr/+ Skin carcinoma
  • methylcholanthrene (MCA)
 Skin

high
HR Hrhr Skin carcinoma
  • methylcholanthrene (MCA)
 Skin

high
HR Hrhr Skin papilloma
  • methylcholanthrene (MCA)
 Skin

100
HR Hrhr/+ Skin papilloma
  • methylcholanthrene (MCA)
 Skin

100
129 Testis - Germ cell teratoma Testis - Germ cell

1
BALB/c Testis - Leydig cell (Interstitial cell) tumor
  • diethylstilbestrol (DES)
 Testis - Leydig cell (Interstitial cell)

high
A Testis - Leydig cell (Interstitial cell) tumor
  • estrogen
 Testis - Leydig cell (Interstitial cell)

observed