Strain SummaryB6.Cg-Gt(ROSA)26Sortm1.3(CAG-tdTomato,-EGFP)Pjen

Strain Name

B6.Cg-Gt(ROSA)26Sortm1.3(CAG-tdTomato,-EGFP)Pjen

Strain Type(s)

congenic

Strain Synonym(s)

RC::FLTG

Description

Transgenic mice on a congenic C57BL/6 background transferred from (129S6/SvEvTac x C57BL/6Ncrl)F1.

Models

23 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Lung carcinoma - large cell neuroendocrine Lung Qfrt Y4 Linear-Cationic polymer Y4 Linear carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

observed - 7

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Sites of Metastasis: Lung

Lung carcinoma - large cell neuroendocrine Lung Qfrt Y4 L5-Cationic polymer Y4 L5 carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

0 - observed

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Sites of Metastasis: not Lung , Lung

Lung carcinoma - large cell neuroendocrine Lung Qfrt Y4Cys-Cationic polymer Y4Cys carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

0

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Lung carcinoma - small cell lung (SCLC) Lung Qfrt Y4 Linear-Cationic polymer Y4 Linear carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

observed - 47

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Lung carcinoma - small cell lung (SCLC) Lung Qfrt Y4 L5-Cationic polymer Y4 L5 carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

observed - 10

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Lung carcinoma - small cell lung (SCLC) Lung Qfrt Y4Cys-Cationic polymer Y4Cys carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

0 - 20

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Lung carcinoma - small cell lung (SCLC) Lymph node Qfrt Y4 Linear-Cationic polymer Y4 Linear carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

7

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Lung hyperplasia - neuroendocrine Lung Qfrt Y4 Linear-Cationic polymer Y4 Linear carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

observed - 7

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Lung hyperplasia - neuroendocrine Lung

0

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Lung hyperplasia - neuroendocrine Lung Qfrt Y4Cys-Cationic polymer Y4Cys carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

0

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Lung hyperplasia - neuroendocrine Lung Qfrt Y4 L5-Cationic polymer Y4 L5 carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

0

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Trachea carcinoma - small cell lung (SCLC) Trachea Qfrt Y4 Linear-Cationic polymer Y4 Linear carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

observed - 60

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Trachea carcinoma - small cell lung (SCLC) Trachea

observed

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Trachea carcinoma - small cell lung (SCLC) Trachea Qfrt Y4 L5-Cationic polymer Y4 L5 carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

30

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Trachea carcinoma - small cell lung (SCLC) Trachea Qfrt Y4Cys-Cationic polymer Y4Cys carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

20

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

(Unspecified organ) tumor (Unspecified organ) Qfrt Y4 Linear-Cationic polymer Y4 Linear carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

67

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Sites of Metastasis: (Unspecified organ) , Liver

(Unspecified organ) tumor (Unspecified organ) Qfrt Y4 L5-Cationic polymer Y4 L5 carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

0 - 30

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Sites of Metastasis: not (Unspecified organ) , not Liver

(Unspecified organ) tumor (Unspecified organ) Qfrt Y4Cys-Cationic polymer Y4Cys carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

0 - 20

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

(Unspecified organ) tumor (Unspecified organ) frt Y4Linear-Cationic polymer Y4Linear carrying RNAP guide for frt.

0

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

(Unspecified organ) tumor (Unspecified organ) frt Y4L5-Cationic polymer Y4L5 carrying RNAP guide for frt.

0

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

(Unspecified organ) tumor (Unspecified organ) Y4Linear-Cationic polymer Y4Linear

0

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

(Unspecified organ) tumor (Unspecified organ) Y4L5-Cationic polymer Y4L5

0

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

(Unspecified organ) tumor (Unspecified organ) Qfrt-RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

0

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121