Strain SummaryC57BL/6-ApcMin/+ Ccr4em1Gpt Foxp3tm4(YFP/icre)Ayr/+
Strain Name |
C57BL/6-ApcMin/+ Ccr4em1Gpt Foxp3tm4(YFP/icre)Ayr/+ |
Strain Type(s) |
chemically induced mutation • targeted mutation (conditional) • targeted mutation (knock-in) |
Strain Synonym(s) |
ApcMin/+ Foxp3Cre Ccr4fl/fl |
Description |
Heterozygous Apc, Foxp3, homozygous Ccr4 mice on a C57BL/6 background with contribution from C57BL/6J, C57BL/6Gpt and 129X1/SvJ and 129S1/Sv. |
Strain Genetics |
ApcMin / Apc+ |
| Ccr4em1Gpt / Ccr4em1Gpt | |
| Foxp3tm4(YFP/icre)Ayr / Foxp3+ |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Intestine - Large Intestine - Colon tumor | Intestine - Large Intestine - Colon |
33 |
References: You S, Cancer Cell 2024 Aug 12;42(8):1415-1433.e12 |
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| Intestine - Small Intestine tumor | Intestine - Small Intestine |
100 |
References: You S, Cancer Cell 2024 Aug 12;42(8):1415-1433.e12 |
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