Strain SummaryC57BL/6-ApcMin/+ Foxp3tm3(HBEGF/GFP)Ayr/+
Strain Name |
C57BL/6-ApcMin/+ Foxp3tm3(HBEGF/GFP)Ayr/+ |
Strain Type(s) |
chemically induced mutation • targeted mutation (knock-in) |
Strain Synonym(s) |
ApcMin/+ Foxp3DTR |
Description |
Heterozygous Apc, Foxp3 mice on a C57BL/6 background with contribution from C57BL/6J, 129X1/SvJ and 129S1/Sv. |
Strain Genetics |
ApcMin / Apc+ |
| Foxp3tm3(HBEGF/GFP)Ayr / Foxp3+ |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Intestine - Large Intestine - Colon tumor | Intestine - Large Intestine - Colon |
observed |
References: You S, Cancer Cell 2024 Aug 12;42(8):1415-1433.e12 |
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| Intestine - Large Intestine - Colon tumor | Intestine - Large Intestine - Colon | Diptheria Toxin (DTX) |
observed |
References: You S, Cancer Cell 2024 Aug 12;42(8):1415-1433.e12 |
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| Intestine tumor | Intestine |
observed |
References: You S, Cancer Cell 2024 Aug 12;42(8):1415-1433.e12 |
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