Strain SummaryC57BL/6-ApcMin/+ Foxp3tm3(HBEGF/GFP)Ayr/+

Strain Name

C57BL/6-ApcMin/+ Foxp3tm3(HBEGF/GFP)Ayr/+

Strain Type(s)

chemically induced mutation  •  targeted mutation (knock-in)

Strain Synonym(s)

ApcMin/+ Foxp3DTR

Description

Heterozygous Apc, Foxp3 mice on a C57BL/6 background with contribution from C57BL/6J, 129X1/SvJ and 129S1/Sv.

Strain Genetics

ApcMin / Apc+
Foxp3tm3(HBEGF/GFP)Ayr / Foxp3+

Models

3 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon

observed

References: You S, Cancer Cell 2024 Aug 12;42(8):1415-1433.e12

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Diptheria Toxin (DTX)

observed

References: You S, Cancer Cell 2024 Aug 12;42(8):1415-1433.e12

Intestine tumor Intestine

observed

References: You S, Cancer Cell 2024 Aug 12;42(8):1415-1433.e12