Strain SummaryC57BL/6-ApcMin/+ Tcratm1Mom

Strain Name

C57BL/6-ApcMin/+ Tcratm1Mom

Strain Type(s)

chemically induced mutation  •  targeted mutation (knockout)

Strain Synonym(s)

ApcMin/+ Tcra-/-

Description

Heterozygous Apc, homozygous Tcra mice on a C57BL/6 background with contribution from C57BL/6J and 129S2/SvPas.

Strain Genetics

ApcMin / Apc+
Tcratm1Mom / Tcratm1Mom

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon

observed - 100

References: You S, Cancer Cell 2024 Aug 12;42(8):1415-1433.e12

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Diptheria Toxin (DTX)

18

References: You S, Cancer Cell 2024 Aug 12;42(8):1415-1433.e12

Intestine - Small Intestine tumor Intestine - Small Intestine

observed - 100

References: You S, Cancer Cell 2024 Aug 12;42(8):1415-1433.e12

Intestine - Small Intestine tumor Intestine - Small Intestine Diptheria Toxin (DTX)

100

References: You S, Cancer Cell 2024 Aug 12;42(8):1415-1433.e12