Strain SummaryC57BL/6-ApcMin Ccr4em2Gpt

Strain Name

C57BL/6-ApcMin Ccr4em2Gpt

Strain Type(s)

chemically induced mutation  •  targeted mutation (knockout)

Strain Synonym(s)

ApcMin/+ Ccr4-/-

Description

Heterozygous Apc, homozygous Ccr4 mice on a C57BL/6 background with contributuion from C57BL/6J and C57BL/6Gpt.

Strain Genetics

ApcMin / Apc+
Ccr4em2Gpt / Ccr4em2Gpt

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon

observed - 56

References: You S, Cancer Cell 2024 Aug 12;42(8):1415-1433.e12

Intestine - Small Intestine tumor Intestine - Small Intestine

observed - 100

References: You S, Cancer Cell 2024 Aug 12;42(8):1415-1433.e12