Strain Summary[not specified]-Mxi1tm1Rdp

Strain Name

[not specified]-Mxi1tm1Rdp

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

mxi1-null  •  mxi1-/-  •  Mxil-/-

Description

Homozygous mice. The genetic background of was not specified. It contained at least C57BL/6J, SJL, and 129/Sv. The reference did not specify which strain was crossed to chimeric mice, so there may or may not be another contributing strain.

Strain Genetics

Mxi1tm1Rdp / Mxi1tm1Rdp

Models

7 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
CNS - Brain - Glial cell glioma CNS - Brain - Glial cell

0

References: Schreiber-Agus N, Nature 1998 Jun 4;393(6684):483-7

Leukocyte - Lymphocyte - B-lymphocyte lymphoma Leukocyte - Lymphocyte - B-lymphocyte

observed

References: Schreiber-Agus N, Nature 1998 Jun 4;393(6684):483-7

Leukocyte lymphoma Leukocyte 9,10-dimethyl-1,2-benzanthracene (DMBA)

observed

References: Schreiber-Agus N, Nature 1998 Jun 4;393(6684):483-7

Prostate gland hyperplasia Prostate gland

55

References: Schreiber-Agus N, Nature 1998 Jun 4;393(6684):483-7

Skin squamous cell carcinoma Skin 9,10-dimethyl-1,2-benzanthracene (DMBA)

observed

References: Schreiber-Agus N, Nature 1998 Jun 4;393(6684):483-7

Spleen - White pulp hyperplasia Spleen - White pulp

33

References: Schreiber-Agus N, Nature 1998 Jun 4;393(6684):483-7

(Unspecified organ) tumor (Unspecified organ) 9,10-dimethyl-1,2-benzanthracene (DMBA)

65

References: Schreiber-Agus N, Nature 1998 Jun 4;393(6684):483-7