Strain SummarySTOCK Cdkn2a^tm1Rdp/+

Strain Name	STOCK Cdkn2a^tm1Rdp/+
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	Cdkn2a^+/- • ink4a^+/- • INK4a^+/-
Description	Heterozygous mice. The genetic background of these mice is a mixture of C57BL/6, 129/Sv, and SJL.
Strain Genetics	List all models in MMHCdb carrying the Cdkn2a^tm1Rdp allele Cdkn2a^tm1Rdp / Cdkn2a⁺

Models
8 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Connective tissue - Fibroblast fibrosarcoma	Connective tissue - Fibroblast	ultraviolet-B radiation (UVB) ⋅ 9,10-dimethyl-1,2-benzanthracene (DMBA)	observed				References: Serrano M, Cell 1996 Apr 5;85(1):27-37
Leukocyte - Lymphocyte lymphoma	Leukocyte - Lymphocyte	MoMuLV - Moloney murine leukemia virus (M-MuLV) (MMLV)				100	References: Lund AH, Nat Genet 2002 Sep;32(1):160-5
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Leukocyte - Monocyte - Macrophage - Histiocyte	MoMuLV - Moloney murine leukemia virus (M-MuLV) (MMLV)				10.81	References: Lund AH, Nat Genet 2002 Sep;32(1):160-5
Leukocyte lymphoma	Leukocyte	ultraviolet-B radiation (UVB) ⋅ 9,10-dimethyl-1,2-benzanthracene (DMBA)	observed				References: Serrano M, Cell 1996 Apr 5;85(1):27-37
Skin - Melanocyte melanoma	Skin - Melanocyte					0	References: Chin L, Genes Dev 1997 Nov 1;11(21):2822-34
Skin squamous cell carcinoma	Skin	ultraviolet-B radiation (UVB) ⋅ 9,10-dimethyl-1,2-benzanthracene (DMBA)		observed			References: Serrano M, Cell 1996 Apr 5;85(1):27-37
(Unspecified organ) tumor	(Unspecified organ)					0	References: Serrano M, Cell 1996 Apr 5;85(1):27-37
(Unspecified organ) tumor	(Unspecified organ)	MoMuLV - Moloney murine leukemia virus (M-MuLV) (MMLV)				100	References: Lund AH, Nat Genet 2002 Sep;32(1):160-5

Models