Strain SummaryAKB6F1-ApcMin/+
Strain Name |
AKB6F1-ApcMin/+ |
Strain Type(s) |
chemically induced mutation • hybrid |
Strain Synonym(s) |
(AKR/J x C57BL/6J)F1-ApcMin/+ • AKR/J x C57BL/6J.Min/+, Min/+ • (AKR X B6) ApcMin/Apc+ • (AKR x B6)F1, Min/+ • (AKR X B6)F1 Min/+ • (AKR X B6)F1Min/+ • (AKR x B6 Min/+) • AKR x B6.Min/+, Min/+ • (AKR x B6-Min ApcMin/Apc+) • (AKR x B6-Min)F1 • (AKR X B6-Min)F1 • (AKR X B6-Min)F1 ApcMin/Apc+ • (AKR X B6-Min)F1 Apc+/ApcMin • ApcMin • Apc+/ApcMin • Min/+ • Min |
Description |
Heterozygous mice - "Min" mutation on a (AKR/J x C57BL/6J)F1 genetic background. |
Strain Genetics |
ApcMin / Apc+ |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Intestine - Large Intestine - Colon adenoma | Intestine - Large Intestine - Colon |
observed |
References: Luongo C, Cancer Res 1994 Nov 15;54(22):5947-52 ⋅ Moser AR, J Cell Biol 1992 Mar;116(6):1517-26 |
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| Intestine - Large Intestine adenoma | Intestine - Large Intestine |
very high |
References: Zhang T, Cancer Res 1997 May 1;57(9):1638-43 |
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| Intestine - Small Intestine - Duodenum adenoma | Intestine - Small Intestine - Duodenum |
observed |
References: Luongo C, Cancer Res 1994 Nov 15;54(22):5947-52 |
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| Intestine - Small Intestine - Ileum adenoma | Intestine - Small Intestine - Ileum |
observed |
References: Luongo C, Cancer Res 1994 Nov 15;54(22):5947-52 |
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| Intestine - Small Intestine - Jejunum adenoma | Intestine - Small Intestine - Jejunum |
observed |
References: Luongo C, Cancer Res 1994 Nov 15;54(22):5947-52 |
|||||
| Intestine - Small Intestine adenoma | Intestine - Small Intestine |
observed - very high |
References: Moser AR, J Cell Biol 1992 Mar;116(6):1517-26 ⋅ Zhang T, Cancer Res 1997 May 1;57(9):1638-43 |
|||||
| Intestine adenoma | Intestine |
very high |
observed - 100 |
References: Luongo C, Cancer Res 1994 Nov 15;54(22):5947-52 ⋅ Luongo C, Genes Chromosomes Cancer 1996 Nov;17(3):194-8 ⋅ Moser AR, J Cell Biol 1992 Mar;116(6):1517-26 ⋅ Moser AR, Proc Natl Acad Sci U S A 1993 Oct 1;90(19):8977-81 ⋅ Shoemaker AR, Cancer Res 1997 May 15;57(10):1999-2006 ⋅ Zhang T, Cancer Res 1997 May 1;57(9):1638-43 |
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| Intestine adenoma | Intestine | gamma-radiation |
100 |
References: Luongo C, Genes Chromosomes Cancer 1996 Nov;17(3):194-8 |
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| Intestine carcinoma | Intestine |
0 |
References: Zhang T, Cancer Res 1997 May 1;57(9):1638-43 |
|||||
| Intestine carcinoma in situ | Intestine |
observed |
References: Shoemaker AR, Cancer Res 1997 May 15;57(10):1999-2006 |
|||||
| Intestine dysplasia | Intestine |
very high |
References: Zhang T, Cancer Res 1997 May 1;57(9):1638-43 |
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| Mammary gland carcinoma | Mammary gland |
20 |
References: Moser AR, Proc Natl Acad Sci U S A 1993 Oct 1;90(19):8977-81 |
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