Strain SummaryC57BL/6 +/+ : 129P2/OlaHsd-Apctm1Rak/+

Strain Name

 C57BL/6 +/+ : 129P2/OlaHsd-Apctm1Rak/+

Strain Type(s)

 chimeric  •  targeted mutation (knockout)

Strain Synonym(s)

 Apc1638  •  Apc1638 chimera

Description

 Chimeras were generated by injecting E14 (129P2/OlaHsd) ES cells with a targeted Apc mutation (called "Apc1638N") into C57BL/6 blastocysts.

Strain Genetics
Apc+ / Apc+
Apctm1Rak / Apc+

Models

9 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Cecum tumor Intestine - Large Intestine - Cecum

0

References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73

Intestine - Large Intestine - Colon - Distal polyp Intestine - Large Intestine - Colon - Distal

56

References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73

Intestine - Large Intestine - Colon - Medial polyp Intestine - Large Intestine - Colon - Medial

11

References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73

Intestine - Large Intestine - Colon - Proximal polyp Intestine - Large Intestine - Colon - Proximal

11

References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73

Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum

11

References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73

Intestine - Small Intestine - Ileum carcinoma Intestine - Small Intestine - Ileum

11

References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73

Intestine - Small Intestine - Jejunum adenoma Intestine - Small Intestine - Jejunum

11

References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73

Intestine - Small Intestine - Jejunum carcinoma Intestine - Small Intestine - Jejunum

11

References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73

Stomach - Glandular tumor Stomach - Glandular

0

References: Fodde R, Proc Natl Acad Sci U S A 1994 Sep 13;91(19):8969-73