Strain SummaryB6;129S7-ApcMin/+ Mlh1tm1Lisk

Strain Name

B6;129S7-ApcMin/+ Mlh1tm1Lisk

Strain Type(s)

chemically induced mutation  •  targeted mutation (knockout)

Strain Synonym(s)

B6,129-ApcMin/+ Mlh1tm1Lisk  •  ApcMin/+ Mlh1-/-  •  Min/+ Mlh1-/-

Description

Mice were heterozygous for the ApcMin allele and homozygous for a targeted mutation of Mlh1. The genetic background was a mixture of C57BL/6J and 129S7/SvEvBrd-Hprtb-m2.

Strain Genetics

ApcMin / Apc+
Mlh1tm1Lisk / Mlh1tm1Lisk

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Connective tissue - Fibroblast desmoid Connective tissue - Fibroblast

36

References: Shoemaker AR, Oncogene 2000 May 25;19(23):2774-9

Intestine adenoma Intestine

very high

References: Shoemaker AR, Oncogene 2000 May 25;19(23):2774-9

Intestine cyst Intestine

very high

References: Shoemaker AR, Oncogene 2000 May 25;19(23):2774-9

Skin - Dermis cyst - epidermoid Skin - Dermis

50

References: Shoemaker AR, Oncogene 2000 May 25;19(23):2774-9