Strain SummaryB6;129S7-ApcMin/+ Mlh1tm1Lisk/+
Strain Name |
B6;129S7-ApcMin/+ Mlh1tm1Lisk/+ |
Strain Type(s) |
chemically induced mutation • targeted mutation (knockout) |
Strain Synonym(s) |
B6,129-ApcMin/+ Mlh1tm1Lisk/+ • ApcMin/+ Mlh1+/- • Min/+ Mlh1+/- |
Description |
Mice were heterozygous for the ApcMin allele and heterozygous for the Mlh1tm1Lisk allele. The genetic background of this strain is a mixture of C57BL/6J and 129S7/SvEvBrd-Hprtb-m2. |
Strain Genetics |
ApcMin / Apc+ |
| Mlh1tm1Lisk / Mlh1+ |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Connective tissue - Fibroblast desmoid | Connective tissue - Fibroblast |
0 |
References: Shoemaker AR, Oncogene 2000 May 25;19(23):2774-9 |
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| Intestine adenoma | Intestine |
very high |
References: Shoemaker AR, Oncogene 2000 May 25;19(23):2774-9 |
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| Intestine cyst | Intestine |
very high |
References: Shoemaker AR, Oncogene 2000 May 25;19(23):2774-9 |
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| Skin - Dermis cyst - epidermoid | Skin - Dermis |
0 |
References: Shoemaker AR, Oncogene 2000 May 25;19(23):2774-9 |
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