Strain SummaryB6;129S7-ApcMin/+ Mlh1tm1Lisk/+

Strain Name

B6;129S7-ApcMin/+ Mlh1tm1Lisk/+

Strain Type(s)

chemically induced mutation  •  targeted mutation (knockout)

Strain Synonym(s)

B6,129-ApcMin/+ Mlh1tm1Lisk/+  •  ApcMin/+ Mlh1+/-  •  Min/+ Mlh1+/-

Description

Mice were heterozygous for the ApcMin allele and heterozygous for the Mlh1tm1Lisk allele. The genetic background of this strain is a mixture of C57BL/6J and 129S7/SvEvBrd-Hprtb-m2.

Strain Genetics

ApcMin / Apc+
Mlh1tm1Lisk / Mlh1+

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Connective tissue - Fibroblast desmoid Connective tissue - Fibroblast

0

References: Shoemaker AR, Oncogene 2000 May 25;19(23):2774-9

Intestine adenoma Intestine

very high

References: Shoemaker AR, Oncogene 2000 May 25;19(23):2774-9

Intestine cyst Intestine

very high

References: Shoemaker AR, Oncogene 2000 May 25;19(23):2774-9

Skin - Dermis cyst - epidermoid Skin - Dermis

0

References: Shoemaker AR, Oncogene 2000 May 25;19(23):2774-9