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Strain SummaryB6;129P2-Apc^Min/+ Msh2^tm1Mak

Strain Name	B6;129P2-Apc^Min/+ Msh2^tm1Mak
Strain Type(s)	chemically induced mutation • targeted mutation (knockout)
Strain Synonym(s)	B6,129-Apc^Min Msh2^tm1Mak • Apc+/- Msh2-/- • Apc^+/-/Msh2^-/-
Description	Mice were heterozygous for the Apc^Min allele and homozygous for the Msh2^tm1Mak allele. The genetic background of these mice was a mixture of C57BL/6J and 129P2/OlaHsd.
Strain Genetics	List all models in MMHCdb carrying the Apc^Min allele Apc^Min / Apc⁺
	List all models in MMHCdb carrying the Msh2^tm1Mak allele Msh2^tm1Mak / Msh2^tm1Mak

Models
17 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon	folate-deficient				observed	References: Song J, Cancer Res 2000 Jun 15;60(12):3191-9
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon	folate-supplemented				observed	References: Song J, Cancer Res 2000 Jun 15;60(12):3191-9
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon					observed - 67	References: Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6
Intestine - Large Intestine - Colon foci - aberrant crypt (ACF)	Intestine - Large Intestine - Colon					very high	References: Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6
Intestine - Large Intestine - Colon foci - dysplastic	Intestine - Large Intestine - Colon	folate-deficient				very high	References: Song J, Cancer Res 2000 Jun 15;60(12):3191-9
Intestine - Large Intestine - Colon foci - dysplastic	Intestine - Large Intestine - Colon	folate-supplemented				very high	References: Song J, Cancer Res 2000 Jun 15;60(12):3191-9
Intestine - Small Intestine - Duodenum adenoma	Intestine - Small Intestine - Duodenum	folate-deficient				very high	References: Song J, Cancer Res 2000 Jun 15;60(12):3191-9
Intestine - Small Intestine - Duodenum adenoma	Intestine - Small Intestine - Duodenum	folate-supplemented				very high	References: Song J, Cancer Res 2000 Jun 15;60(12):3191-9
Intestine - Small Intestine - Ileum adenoma	Intestine - Small Intestine - Ileum	folate-deficient				very high	References: Song J, Cancer Res 2000 Jun 15;60(12):3191-9
Intestine - Small Intestine - Ileum adenoma	Intestine - Small Intestine - Ileum	folate-supplemented				very high	References: Song J, Cancer Res 2000 Jun 15;60(12):3191-9
Intestine - Small Intestine - Jejunum adenoma	Intestine - Small Intestine - Jejunum	folate-deficient				very high	References: Song J, Cancer Res 2000 Jun 15;60(12):3191-9
Intestine - Small Intestine - Jejunum adenoma	Intestine - Small Intestine - Jejunum	folate-supplemented				very high	References: Song J, Cancer Res 2000 Jun 15;60(12):3191-9
Intestine - Small Intestine adenoma	Intestine - Small Intestine	folate-deficient				very high	References: Song J, Cancer Res 2000 Jun 15;60(12):3191-9
Intestine - Small Intestine adenoma	Intestine - Small Intestine	folate-supplemented				very high	References: Song J, Cancer Res 2000 Jun 15;60(12):3191-9
Intestine - Small Intestine adenoma	Intestine - Small Intestine					observed	References: Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6
Intestine carcinoma	Intestine					0	References: Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6
Leukocyte lymphoma	Thymus					29	References: Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6