Strain SummarySTOCK Cdkn2atm1Rdp Tg(Tyr-HRAS)#Lc

Strain Name

STOCK Cdkn2atm1Rdp Tg(Tyr-HRAS)#Lc

Strain Type(s)

targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

try-ras ink4a-/-  •  STOCK Tg(Tyr-HRAS)39,60Lc Cdkn2atm1Rdp  •  STOCK Tg(Tyr-HRAS)#Lc Cdkn2atm1Rdp  •  TR39 and TR60 ink4a-/-

Description

Mice were homozygous for the Cdkn2a mutant allele and carried the transgene. This STOCK genetic background was a mixture of C57BL/6, CBA, and "129/Sv" (substrain unspecified).

Strain Genetics

Tg(Tyr-HRAS)#Lc
Cdkn2atm1Rdp / Cdkn2atm1Rdp

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Skin - Melanocyte melanoma Skin - Melanocyte

observed

References: Chin L, Genes Dev 1997 Nov 1;11(21):2822-34