Strain SummarySTOCK Tg(Tyr-HRAS)60Lc

Strain Name

STOCK Tg(Tyr-HRAS)60Lc

Strain Type(s)

transgenic

Strain Synonym(s)

activated H-rasG12V  •  ink4a+/+ transgenic  •  tyr-ras  •  TR60  •  Tyr-H-RASV12G  •  Tyr-RAS  •  Tyr-RAS p53+/+

Description

This STOCK genetic background was a mixture of C57BL/6J, CBA/J, "129/Sv" (substrain unspecified), and SJL/J.

Strain Genetics

Tg(Tyr-HRAS)60Lc
Trp53+ / Trp53+
Cdkn2a+ / Cdkn2a+

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Skin - Melanocyte melanoma Skin - Melanocyte

0 - 2.4

References: Bardeesy N, Mol Cell Biol 2001 Mar;21(6):2144-53   ⋅   Chin L, Genes Dev 1997 Nov 1;11(21):2822-34