Strain Summary[not specified]-Cdkn2a^tm1Rdp Tg(Tyr-HRAS)60Lc

Strain Name	[not specified]-Cdkn2a^tm1Rdp Tg(Tyr-HRAS)60Lc
Strain Type(s)	targeted mutation (knockout) • transgenic
Strain Synonym(s)	[not specified]-Tg(Tyr-HRAS)60Lc Cdkn2a^tm1Rdp • Tyr-H-RAS^V12G INK4a^Δ2/3-/- • Tyr-RAS INK4a^Δ2/3-/- • Tyr-RAS INK4a^Δ2/3 null
Description	Mice homozygous for a targeted mutation of Cdkn2a (INK4a-ARF) and transgenic for an activated human HRAS (G12V) oncogene under control of the melanocyte-specific mouse tyrosinase promoter. Genetic background not specified.
Strain Genetics	List all models in MMHCdb carrying the Tg(Tyr-HRAS)60Lc allele Tg(Tyr-HRAS)60Lc
	List all models in MMHCdb carrying the Cdkn2a^tm1Rdp allele Cdkn2a^tm1Rdp / Cdkn2a^tm1Rdp

Models
1 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Skin - Melanocyte melanoma	Skin - Melanocyte			observed			References: Bardeesy N, Mol Cell Biol 2001 Mar;21(6):2144-53

Models