Strain SummaryFVB;129S-Tg(C3-1-TAg)cJeg Trp53tm1Tyj

Strain Name

FVB;129S-Tg(C3-1-TAg)cJeg Trp53tm1Tyj

Strain Type(s)

targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

C3(1)/TAG, p53-/-  •  FVB;129S-TgN(C3-1-TAg)cJeg Trp53tm1Tyj  •  C3(1)/TAg+/-;p53-/-  •  C3(1)/TAg;p53-/-  •  p53-/- TAG  •  p53-/- TAG SV129/FVB-N  •  TAG-/+, p53-/-

Description

Mice are hemizygous for the transgene and homozygous for the Trp53tm1Tyj allele. The genetic background of these mice is a mixture of FVB/N and 129S (a mixture of 129 substrains including 129S2/SvPas and probably 129S4/SvJae).

Strain Genetics

Tg(C3-1-TAg)cJeg
Trp53tm1Tyj / Trp53tm1Tyj

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Leukocyte lymphoma Leukocyte

very high

References: Maroulakou IG, Mol Carcinog 1997 Oct;20(2):168-74

Mammary gland carcinoma Mammary gland

observed

References: Shibata MA, EMBO J 1999 May 17;18(10):2692-701