Strain SummaryFVB/N-Tg(MMTV-Erbb2)NK1Mul
Strain Name |
FVB/N-Tg(MMTV-Erbb2)NK1Mul |
Strain Type(s) |
transgenic |
Strain Synonym(s) |
FVB/N-TgN(MMTV-Erbb2)NK1Mul • MMTV-neu • neu • MMTV/c-neu • MMTV-neu • NK/+ • TG.NK |
Description |
The original founder of this line (called "TG.NK) carried 2 insertions of the transgene which, through breeding, were separated to 2 distinct lines, called "TG.NK" and "TG.NM". |
Strain Genetics |
Tg(MMTV-Erbb2)NK1Mul |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Mammary gland adenocarcinoma | Mammary gland |
observed |
References: Muller WJ, Cell 1988 Jul 1;54(1):105-15 ⋅ Ray D, Cancer Res 2007 Feb 1;67(3):984-91 |
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| Mammary gland tumor | Mammary gland |
50 - 96 |
References: Cardiff RD, Am J Pathol 1991 Sep;139(3):495-501 ⋅ Ray D, Cancer Res 2007 Feb 1;67(3):984-91 |
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