Strain SummaryB6;129S1-Cdkn2btm1Bbd/+

Strain Name

B6;129S1-Cdkn2btm1Bbd/+

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

P15INK4b (+/-)

Description

Mice heterozygous for a targeted mutation of Cdkn2b (p15INK4b). The genetic background was a mix of C57BL/6 and 129S1/Sv-p+ Tyr+ Kitl+.

Strain Genetics

Cdkn2btm1Bbd / Cdkn2b+
Cdkn2c+ / Cdkn2c+

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

1

References: Latres E, EMBO J 2000 Jul 3;19(13):3496-506

Skin papilloma Skin ultraviolet-B radiation (UVB)   ⋅   dimethylbenzanthracene (DMBA)

2.6

References: Latres E, EMBO J 2000 Jul 3;19(13):3496-506