Strain SummaryB6;129S1-Cdkn2c^tm1Bbd

Strain Name	B6;129S1-Cdkn2c^tm1Bbd
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	P18^INK4c (-/-) • P18INK4c (-/-)
Description	Mice homozygous for a targeted mutation of Cdkn2c (p18INK4c). The genetic background was a mix of C57BL/6 and 129S1/Sv-p⁺ Tyr⁺ Kitl⁺.
Strain Genetics	List all models in MMHCdb carrying the Cdkn2c^tm1Bbd allele Cdkn2c^tm1Bbd / Cdkn2c^tm1Bbd
	Cdkn2b⁺ / Cdkn2b⁺

Models
9 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Adrenal gland - Medulla pheochromocytoma	Adrenal gland - Medulla					10	References: Latres E, EMBO J 2000 Jul 3;19(13):3496-506
Kidney carcinoma	Kidney					1.7	References: Latres E, EMBO J 2000 Jul 3;19(13):3496-506
Leukocyte - Lymphocyte - B-lymphocyte lymphoma	Leukocyte - Lymphocyte - B-lymphocyte					3.4	References: Latres E, EMBO J 2000 Jul 3;19(13):3496-506
Leukocyte - Lymphocyte lymphoma	Thymus					1.7	References: Latres E, EMBO J 2000 Jul 3;19(13):3496-506
Mammary gland hyperplasia	Mammary gland		30				References: Latres E, EMBO J 2000 Jul 3;19(13):3496-506
Pituitary gland hyperplasia	Pituitary gland					high	References: Latres E, EMBO J 2000 Jul 3;19(13):3496-506
Pituitary gland tumor	Pituitary gland					40	References: Latres E, EMBO J 2000 Jul 3;19(13):3496-506
Testis tumor	Testis					observed	References: Latres E, EMBO J 2000 Jul 3;19(13):3496-506
(Unspecified organ) angiosarcoma	(Unspecified organ)					3.4	References: Latres E, EMBO J 2000 Jul 3;19(13):3496-506

Models