Strain SummaryB6;129S1-Cdkn2b^tm1Bbd Cdkn2c^tm1Bbd

Strain Name	B6;129S1-Cdkn2b^tm1Bbd Cdkn2c^tm1Bbd
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	P15^INK4b;P18^INK4c [(-/-);(-/-)] • P15INK4b;P18INK4c [(-/-);(-/-)]
Description	Mice homozygous for targeted mutations of Cdkn2b (p15INK4b) and Cdkn2c (p18INK4c). The genetic background was a mix of C57BL/6 and 129S1/Sv-p⁺ Tyr⁺ Kitl⁺.
Strain Genetics	List all models in MMHCdb carrying the Cdkn2c^tm1Bbd allele Cdkn2c^tm1Bbd / Cdkn2c^tm1Bbd
	List all models in MMHCdb carrying the Cdkn2b^tm1Bbd allele Cdkn2b^tm1Bbd / Cdkn2b^tm1Bbd

Models
5 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Adrenal gland - Medulla pheochromocytoma	Adrenal gland - Medulla					2.5	References: Latres E, EMBO J 2000 Jul 3;19(13):3496-506
Leukocyte tumor	Leukocyte					5	References: Latres E, EMBO J 2000 Jul 3;19(13):3496-506
Pituitary gland - Pars intermedia adenoma	Pituitary gland - Pars intermedia					48	References: Latres E, EMBO J 2000 Jul 3;19(13):3496-506
Testis tumor	Testis			4.2			References: Latres E, EMBO J 2000 Jul 3;19(13):3496-506
(Unspecified organ) angiosarcoma	(Unspecified organ)					observed	References: Latres E, EMBO J 2000 Jul 3;19(13):3496-506

Models