Strain SummarySTOCK Tg(MtTGFA)42Lmb Trp53tm1Tyj

Strain Name

STOCK Tg(MtTGFA)42Lmb Trp53tm1Tyj

Strain Type(s)

targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

B6;CD-1-Tg(MtTGFA)42Lmb Trp53tm1Tyj  •  B6;CD-1-TgN(MtTGFA)42Lmb Trp53tm1Tyj  •  MT-TGFα p53-/-  •  MT42 p53-/-  •  MT42 p53-/- CD1/C57BL/6

Description

Mice were homozygous for the Trp53 mutant allele and carried the Tg(MtTGFA)42Lmb transgene. This STOCK genetic background was a mixture predominantly of C57BL/6 and CD-1 and also included 129S2/SvPas and possibly some 129/Sv and SJL.

Strain Genetics

Cdkn2a+ / Cdkn2a+
Trp53tm1Tyj / Trp53tm1Tyj
Tg(MtTGFA)42Lmb

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Pancreas cystadenoma - serous Pancreas

27

References: Bardeesy N, Mol Cell Biol 2002 Jan;22(2):635-43

Pancreas metaplasia - tubular Pancreas

observed

References: Bardeesy N, Mol Cell Biol 2002 Jan;22(2):635-43