Strain SummarySTOCK Cdkn2a^tm1Rdp Tg(MtTGFA)42Lmb Trp53^tm1Tyj

Strain Name	STOCK Cdkn2a^tm1Rdp Tg(MtTGFA)42Lmb Trp53^tm1Tyj
Strain Type(s)	targeted mutation (knockout) • transgenic
Strain Synonym(s)	B6;CD-1-Tg(MtTGFA)42Lmb Cdkn2a^tm1Rdp Trp53^tm1Tyj • B6;CD-1-TgN(MtTGFA)42Lmb Cdkn2a^tm1Rdp Trp53^tm1Tyj • MT-TGFα p53^-/- Ink4a/Arf^-/- • MT42 Ink/Arf^-/- p53^-/- • MT42 Ink/Arf^-/- p53^-/- CD1/C57BL/6 • STOCK Tg(MtTGFA)42Lmb Cdkn2a^tm1Rdp Trp53^tm1Tyj
Description	Mice were homozygous for the Cdkn2a and Trp53 mutant alleles and carried the Tg(MtTGFA)42Lmb transgene. This STOCK genetic background was a mixture predominantly of C57BL/6 and CD-1 and also included 129/Sv, 129S2/SvPas, and SJL.
Strain Genetics	List all models in MMHCdb carrying the Trp53^tm1Tyj allele Trp53^tm1Tyj / Trp53^tm1Tyj
	List all models in MMHCdb carrying the Tg(MtTGFA)42Lmb allele Tg(MtTGFA)42Lmb
	List all models in MMHCdb carrying the Cdkn2a^tm1Rdp allele Cdkn2a^tm1Rdp / Cdkn2a^tm1Rdp

Models
2 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Pancreas cystadenoma - serous	Pancreas					25	References: Bardeesy N, Mol Cell Biol 2002 Jan;22(2):635-43
Pancreas metaplasia - tubular	Pancreas					observed	References: Bardeesy N, Mol Cell Biol 2002 Jan;22(2):635-43

Models