Strain Summary[not specified]-Cdk4tm1.1Bbd/+ Trp53tm1Tyj
Strain Name |
[not specified]-Cdk4tm1.1Bbd/+ Trp53tm1Tyj |
Strain Type(s) |
targeted mutation (knock-in) • targeted mutation (knockout) |
Strain Synonym(s) |
Cdk4+/R24C;p53-/- |
Description |
Mice were heterozygous for the Cdk4 allele and homozygous for the Trp53 allele. The genetic background of these mice was not specified, but it contained at least some 129X1/SvJ, some 129S1/Sv, some 129S4/SvJae, and some outbred CD-1. |
Strain Genetics |
Cdk4tm1.1Bbd / Cdk4+ |
| Trp53tm1Tyj / Trp53tm1Tyj |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Germ cell (sex not specified) teratoma | Germ cell (sex not specified) |
0 |
References: Sotillo R, EMBO J 2001 Dec 3;20(23):6637-47 |
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| Leukocyte lymphoma | Leukocyte |
73 |
References: Sotillo R, EMBO J 2001 Dec 3;20(23):6637-47 |
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| Mesodermal cell/mesoblast sarcoma | Mesodermal cell/mesoblast |
40 |
References: Sotillo R, EMBO J 2001 Dec 3;20(23):6637-47 |
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| (Unspecified organ) tumor | (Unspecified organ) |
100 |
References: Sotillo R, EMBO J 2001 Dec 3;20(23):6637-47 |
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