Strain Summary[not specified]-Trp53^tm1Tyj

Strain Name	[not specified]-Trp53^tm1Tyj
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	Cdk4^+/+;p53^-/-
Description	Mice were homozygous for the Trp53^tm1Tyj allele. The genetic background of these mice was not specified, but it contained at least some 129S2/SvPas and possibly some 129X1/SvJ, some 129S1/Sv and/or some outbred CD-1.
Strain Genetics	Cdk4⁺ / Cdk4⁺
	List all models in MMHCdb carrying the Trp53^tm1Tyj allele Trp53^tm1Tyj / Trp53^tm1Tyj

Models
4 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Germ cell (sex not specified) teratoma	Germ cell (sex not specified)					0	References: Sotillo R, EMBO J 2001 Dec 3;20(23):6637-47
Leukocyte lymphoma	Leukocyte					82	References: Sotillo R, EMBO J 2001 Dec 3;20(23):6637-47
Mesodermal cell/mesoblast sarcoma	Mesodermal cell/mesoblast					18	References: Sotillo R, EMBO J 2001 Dec 3;20(23):6637-47
(Unspecified organ) tumor	(Unspecified organ)					100	References: Sotillo R, EMBO J 2001 Dec 3;20(23):6637-47

Models