Strain Summary[not specified]-Cdk4tm1.1Bbd/+ Cdkn1btm1Mlf

Strain Name

[not specified]-Cdk4tm1.1Bbd/+ Cdkn1btm1Mlf

Strain Type(s)

targeted mutation (knock-in)  •  targeted mutation (knockout)

Strain Synonym(s)

Cdk4+/R24C;p27Kip1-/-

Description

Mice were heterozygous for the Cdk4 allele and homozygous for the Cdkn1b allele. The genetic background of these mice was not specified, but it contained at least some 129X1/SvJ, some 129S1/Sv, some 129S4/SvJaeSor, and some outbred CD-1.

Strain Genetics

Cdk4tm1.1Bbd / Cdk4+
Cdkn1btm1Mlf / Cdkn1btm1Mlf

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Pituitary gland tumor Pituitary gland

observed

References: Sotillo R, EMBO J 2001 Dec 3;20(23):6637-47