Strain Summary[not specified]-Cdk4tm1.1Bbd Cdkn1btm1Mlf/+
Strain Name |
[not specified]-Cdk4tm1.1Bbd Cdkn1btm1Mlf/+ |
Strain Type(s) |
targeted mutation (knock-in) • targeted mutation (knockout) |
Strain Synonym(s) |
Cdk4R24C/R24C;p27Kip1+/- |
Description |
Mice were homozgyous for the Cdk4 and heterozygous for the Cdkn1b mutant alleles. The genetic background of these mice was not specified, but it contained at least some 129X1/SvJ, some 129S1/Sv, some 129S4/SvJaeSor, and some outbred CD-1. |
Strain Genetics |
Cdk4tm1.1Bbd / Cdk4tm1.1Bbd |
| Cdkn1btm1Mlf / Cdkn1b+ |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Pituitary gland tumor | Pituitary gland |
observed |
References: Sotillo R, EMBO J 2001 Dec 3;20(23):6637-47 |
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