Strain SummaryC57BL/6-Mmp9tm1Tvu Tg(RIP1-Tag)2Dh

Strain Name

 C57BL/6-Mmp9tm1Tvu Tg(RIP1-Tag)2Dh

Strain Type(s)

 targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

 B6.Cg-TgN(RIP1-Tag)2Dh Mmp9tm1Tvu  •  B6.Cg-Tg(RIP1-Tag)2Dh Mmp9tm1Tvu  •  C57BL/6-Tg(RIP1-Tag)2Dh Mmp9tm1Tvu  •  MMP-9-deficient RIP1-Tag2  •  RIP1-Tag2 MMP-9 -/-  •  RIP-Tag2, MMP-9-ko/ko

Description

 These mice carry the Tg(RIP1-Tag)2Dh transgene and are homozygous for the Mmp9tm1Tvu allele. They are the product of an intercross between strains on a predominantly C57BL/6 background.

Strain Genetics

 Mmp9tm1Tvu / Mmp9tm1Tvu
Tg(RIP1-Tag)2Dh

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Pancreas - Islet of Langerhans - Beta cell adenoma Pancreas - Islet of Langerhans - Beta cell

very high

References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44

Pancreas - Islet of Langerhans - Beta cell carcinoma Pancreas - Islet of Langerhans - Beta cell

very high

References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44

Pancreas - Islet of Langerhans - Beta cell hyperplasia Pancreas - Islet of Langerhans - Beta cell

very high

References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44

Pancreas - Islet of Langerhans - Beta cell tumor Pancreas - Islet of Langerhans - Beta cell

very high

References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44