Strain SummaryC57BL/6-Mmp2^tm1Ito Tg(RIP1-Tag)2Dh

Strain Name	C57BL/6-Mmp2^tm1Ito Tg(RIP1-Tag)2Dh
Strain Type(s)	targeted mutation (knockout) • transgenic
Strain Synonym(s)	B6.Cg-TgN(RIP1-Tag)2Dh Mmp2^tm1Ito • B6.Cg-Tg(RIP1-Tag)2Dh Mmp2^tm1Ito • C57BL/6-Tg(RIP1-Tag)2Dh Mmp2^tm1Ito • MMP-2-deficient RIP1-Tag2 • RIP1-Tag2 MMP-2 -/- • RIP1-Tag2, MMP-2-ko/ko
Description	These mice carry the Tg(RIP1-Tag)2Dh transgene and are homozygous for the Mmp2^tm1Ito allele. They are the product of an intercross between strains on a predominantly C57BL/6 background.
Strain Genetics	List all models in MMHCdb carrying the Mmp2^tm1Ito allele Mmp2^tm1Ito / Mmp2^tm1Ito
	List all models in MMHCdb carrying the Tg(RIP1-Tag)2Dh allele Tg(RIP1-Tag)2Dh

Models
4 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Pancreas - Islet of Langerhans - Beta cell adenoma	Pancreas - Islet of Langerhans - Beta cell					very high	References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44
Pancreas - Islet of Langerhans - Beta cell carcinoma	Pancreas - Islet of Langerhans - Beta cell					very high	References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44
Pancreas - Islet of Langerhans - Beta cell hyperplasia	Pancreas - Islet of Langerhans - Beta cell					very high	References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44
Pancreas - Islet of Langerhans - Beta cell tumor	Pancreas - Islet of Langerhans - Beta cell					very high	References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44

Models