Strain SummaryC57BL/6J-Tg(RIP1-Tag)2Dh Tg(Ins2-cre)25Mgn Vegfa^tm2Gne

Strain Name	C57BL/6J-Tg(RIP1-Tag)2Dh Tg(Ins2-cre)25Mgn Vegfa^tm2Gne
Strain Type(s)	targeted mutation (conditional) • transgenic
Strain Synonym(s)	B6.Cg-TgN(RIP1-Tag)2Dh TgN(Ins2-cre)25Mgn Vegfa^tm2Gne • B6.Cg-Tg(RIP1-Tag)2Dh Tg(Ins2-cre)25Mgn Vegfa^tm2Gne • RIP1-Tag2/Cre;Vegf^fl/fl • RIP-1-Tag2;RIP-Cre;Vegf^fl/fl • RIP1-Tag2;RIP-Cre;Vegf^fl/fl
Description	Mice carry the Tg(RIP1-Tag)2Dh and Tg(Ins2-Cre)25Mgn transgenes and are homozygous for the Vegfa^tm2Gne conditional allele. These mice are the product of an intercross between strains on a predominantly C57BL/6J background.
Strain Genetics	List all models in MMHCdb carrying the Vegfa^tm2Gne allele Vegfa^tm2Gne / Vegfa^tm2Gne
	List all models in MMHCdb carrying the Tg(Ins2-cre)25Mgn allele Tg(Ins2-cre)25Mgn
	List all models in MMHCdb carrying the Tg(RIP1-Tag)2Dh allele Tg(RIP1-Tag)2Dh

Models
2 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Pancreas - Islet of Langerhans - Beta cell hyperplasia	Pancreas - Islet of Langerhans - Beta cell					observed	References: Inoue M, Cancer Cell 2002 Mar;1(2):193-202
Pancreas - Islet of Langerhans - Beta cell tumor	Pancreas - Islet of Langerhans - Beta cell					observed	References: Inoue M, Cancer Cell 2002 Mar;1(2):193-202

Models