Strain Summary129/Sv-Smad3^tm1Par

Strain Name	129/Sv-Smad3^tm1Par
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	129.129S4(B6)-Madh3^tm1Par • 129.129S4(B6)-Smad3^tm1Par • 129.Cg(B6)-Smad3^tm1Par • 129.Cg-Smad3^tm1Par • Smad3-/- • Smad3-/- p27+/+
Description	Homozygous mice. These mice are the product of an intercross between strains on a predominantly 129/Sv (substrain not specified) background.
Strain Genetics	Cdkn1b⁺ / Cdkn1b⁺
	List all models in MMHCdb carrying the Smad3^tm1Par allele Smad3^tm1Par / Smad3^tm1Par

Models
5 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Large Intestine - Cecum adenocarcinoma	Intestine - Large Intestine - Cecum				observed		References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68
Intestine - Large Intestine - Cecum adenoma	Intestine - Large Intestine - Cecum				observed		References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68
Intestine - Large Intestine - Colon adenocarcinoma	Intestine - Large Intestine - Colon				observed		References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon				observed		References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68
(Unspecified organ) tumor	(Unspecified organ)				observed		References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68

Models