Strain SummaryB6;129P2-ApcMin/+

Strain Name

B6;129P2-ApcMin/+

Strain Type(s)

chemically induced mutation

Strain Synonym(s)

Apc(+/-)Msh2(+/+)  •  Apc+/-/Msh2+/+  •  Min

Description

Heterozygous mice. Background is a mix of C57BL/6J and 129P2/OlaHsd.

Strain Genetics

ApcMin / Apc+
Msh2+ / Msh2+

Models

8 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Cecum tumor Intestine - Large Intestine - Cecum

observed

0

References: Naigamwalla D, Cancer Res 2000 Dec 15;60(24):6856-8

Intestine - Large Intestine - Cecum tumor Intestine - Large Intestine - Cecum polyethylene glycol 8000 (PEG 8000)

observed

observed

References: Naigamwalla D, Cancer Res 2000 Dec 15;60(24):6856-8

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon

29

0

observed

References: Naigamwalla D, Cancer Res 2000 Dec 15;60(24):6856-8   ⋅   Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon polyethylene glycol 8000 (PEG 8000)

75

17

References: Naigamwalla D, Cancer Res 2000 Dec 15;60(24):6856-8

Intestine - Large Intestine - Colon foci - aberrant crypt (ACF) Intestine - Large Intestine - Colon

observed

References: Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6

Intestine - Small Intestine adenoma Intestine - Small Intestine

observed

observed

observed

References: Naigamwalla D, Cancer Res 2000 Dec 15;60(24):6856-8   ⋅   Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6

Intestine - Small Intestine adenoma Intestine - Small Intestine polyethylene glycol 8000 (PEG 8000)

observed

observed

References: Naigamwalla D, Cancer Res 2000 Dec 15;60(24):6856-8

Intestine carcinoma Intestine

0

References: Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6