Strain SummaryB6;129P2-Apc^Min/+ Msh2^tm1Mak/+

Strain Name	B6;129P2-Apc^Min/+ Msh2^tm1Mak/+
Strain Type(s)	chemically induced mutation • targeted mutation (knockout)
Strain Synonym(s)	Apc(+/-)Msh2(+/-) • Apc^+/-/Msh2^+/-
Description	Mice heterozygous for both the Apc^Min and Msh2^tm1Mak alleles. The genetic background was a mix of C57BL/6J and 129P2/OlaHsd.
Strain Genetics	List all models in MMHCdb carrying the Apc^Min allele Apc^Min / Apc⁺
	List all models in MMHCdb carrying the Msh2^tm1Mak allele Msh2^tm1Mak / Msh2⁺

Models
8 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Large Intestine - Cecum tumor	Intestine - Large Intestine - Cecum		observed	observed			References: Naigamwalla D, Cancer Res 2000 Dec 15;60(24):6856-8
Intestine - Large Intestine - Cecum tumor	Intestine - Large Intestine - Cecum	polyethylene glycol 8000 (PEG 8000)	observed	0			References: Naigamwalla D, Cancer Res 2000 Dec 15;60(24):6856-8
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon		0	0		observed	References: Naigamwalla D, Cancer Res 2000 Dec 15;60(24):6856-8 ⋅ Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon	polyethylene glycol 8000 (PEG 8000)	71	0			References: Naigamwalla D, Cancer Res 2000 Dec 15;60(24):6856-8
Intestine - Large Intestine - Colon foci - aberrant crypt (ACF)	Intestine - Large Intestine - Colon					observed	References: Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6
Intestine - Small Intestine adenoma	Intestine - Small Intestine		observed	observed		observed	References: Naigamwalla D, Cancer Res 2000 Dec 15;60(24):6856-8 ⋅ Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6
Intestine - Small Intestine adenoma	Intestine - Small Intestine	polyethylene glycol 8000 (PEG 8000)	observed	observed			References: Naigamwalla D, Cancer Res 2000 Dec 15;60(24):6856-8
Intestine carcinoma	Intestine					0	References: Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6

Models