Strain SummaryB6.129S7
Strain Name |
B6.129S7 |
Strain Type(s) |
other |
Strain Synonym(s) |
B6.129 • C57BL/6TacfBR-[KO] p53 N5 wild type mice • C57Bl/6Tac-[KO]Trp53N5-W • p53+/+ • p53+/+ Wild-type • wild type • wild-type • wild-type p53+/+ |
Description |
Wild type mice. The genetic background of these mice is congenic for C57BL/6NTac with possibly some contribution from 129S7/SvEvBrd-Hprt+. Mice were purchased from Taconic. |
Strain Genetics |
|
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Blood vessel hemangioma | Liver |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
| Blood vessel hemangioma | Heart |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
| Blood vessel hemangiosarcoma | Spleen |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
| Blood vessel hemangiosarcoma | Liver |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
| Blood vessel hemangiosarcoma | Abdominal cavity |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
| Kidney transitional cell hyperplasia | Kidney |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
| Kidney transitional cell hyperplasia | Kidney | diethylhexylphthalate (DEHP) |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
| Kidney transitional cell papilloma | Kidney |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
| Kidney transitional cell papilloma | Kidney | diethylhexylphthalate (DEHP) |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
| Leukocyte lymphoma | Thymus |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
| Leukocyte lymphoma | Leukocyte |
0 |
0 - 6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
| Leukocyte lymphoma | Leukocyte | cyclophosphamide (Cytoxan) |
0 |
20 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
| Leukocyte lymphoma | Leukocyte | Cyclosporin A |
20 - 60 |
0 - 33.3 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
| Liver hepatocellular carcinoma | Liver |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
| Liver hyperplasia - oval cell | Liver |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
| Liver tumor | Liver |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
| Liver tumor | Liver | chloroform |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
| Lung adenoma | Lung |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
| Mesodermal cell/mesoblast sarcoma | Subcutis |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
| Pituitary gland - Pars distalis adenoma | Pituitary gland - Pars distalis |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
| Pituitary gland - Pars distalis adenoma | Pituitary gland - Pars distalis | diethylstilbestrol (DES) |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
| Pituitary gland - Pars distalis hyperplasia | Pituitary gland - Pars distalis |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
| Pituitary gland - Pars distalis hyperplasia | Pituitary gland - Pars distalis | 17beta-estradiol (E2) |
33.3 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
| Pituitary gland - Pars distalis hyperplasia - diffuse | Pituitary gland - Pars distalis |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
| Pituitary gland - Pars distalis hyperplasia - diffuse | Pituitary gland - Pars distalis | diethylstilbestrol (DES) |
100 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
| Pituitary gland - Pars distalis hyperplasia - nodular | Pituitary gland - Pars distalis |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
| Pituitary gland - Pars distalis hyperplasia - nodular | Pituitary gland - Pars distalis | diethylstilbestrol (DES) |
6.7 - 14.3 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
| Pituitary gland - Pars intermedia adenoma | Pituitary gland - Pars intermedia |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
| Pituitary gland - Pars intermedia adenoma | Pituitary gland - Pars intermedia | diethylstilbestrol (DES) |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
| Pituitary gland - Pars intermedia hyperplasia - diffuse | Pituitary gland - Pars intermedia |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
| Pituitary gland - Pars intermedia hyperplasia - diffuse | Pituitary gland - Pars intermedia | diethylstilbestrol (DES) |
100 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
| Pituitary gland adenoma | Pituitary gland |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
| Pituitary gland adenoma | Pituitary gland | 17beta-estradiol (E2) |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
| Pituitary gland hyperplasia - focal | Pituitary gland |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
| Pituitary gland hyperplasia - focal | Pituitary gland | 17beta-estradiol (E2) |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
| Prostate gland adenoma | Prostate gland |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
| Prostate gland hyperplasia - focal | Prostate gland |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
| Testis - Leydig cell (Interstitial cell) hyperplasia | Testis - Leydig cell (Interstitial cell) |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
| Testis - Leydig cell (Interstitial cell) hyperplasia | Testis - Leydig cell (Interstitial cell) | diethylstilbestrol (DES) |
15.4 - 20 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
| Testis - Leydig cell (Interstitial cell) tumor | Testis - Leydig cell (Interstitial cell) |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
| Testis - Leydig cell (Interstitial cell) tumor | Testis - Leydig cell (Interstitial cell) | diethylstilbestrol (DES) |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
| Ureter hyperplasia | Ureter |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
| Ureter hyperplasia | Ureter | diethylhexylphthalate (DEHP) |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
| Urinary bladder transitional cell carcinoma | Urinary bladder |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
| Urinary bladder transitional cell carcinoma | Urinary bladder | p-cresidine |
6.7 |
6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
| (Unspecified organ) tumor | (Unspecified organ) |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||