Strain SummaryVM.129-Trp53^tm1Brd/?

Strain Name	VM.129-Trp53^tm1Brd/?
Strain Type(s)	congenic • targeted mutation (knockout)
Strain Synonym(s)	p53-deficient • VM.129(B6)-Trp53^tm1Brd/? • VM (-/-) or VM (+/-)
Description	Pooled heterozygotes and homozygotes. This mutation had been backcrossed onto VM. The mutant allele was originally generated in "129/Sv" and had been crossed to C57BL/6 prior to the backcrossing.
Strain Genetics	List all models in MMHCdb carrying the Trp53^tm1Brd allele Trp53^tm1Brd / Trp53^?

Models
3 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Leukocyte lymphoma - non-Hodgkin	Leukocyte				50		References: van Meyel DJ, Int J Oncol 1998 Nov;13(5):917-22 Sites of Metastasis: not Pancreas , not Salivary gland , not Seminal vesicle , not Testis , Adrenal gland , Bone marrow , CNS - Meninges , Heart , Kidney , Liver , Lung , Lymph node , Ovary , Spleen , Thymus
Leukocyte lymphoma - non-Hodgkin	Thymus				39		References: van Meyel DJ, Int J Oncol 1998 Nov;13(5):917-22
Leukocyte lymphoma - non-Hodgkin	Spleen				11		References: van Meyel DJ, Int J Oncol 1998 Nov;13(5):917-22

Models