Strain Summary[not specified]-Brca1tm1Cxd/Brca1tm2Cxd Tg(KRT5-cre)5132Jlj Tg(KRT5-E2F1)2Dgj

Strain Name

[not specified]-Brca1tm1Cxd/Brca1tm2Cxd Tg(KRT5-cre)5132Jlj Tg(KRT5-E2F1)2Dgj

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

K5 E2F1.1:K5 Cre:Brca1co/-  •  K5 E2F1:K5 Cre:Brca1co/-  •  [not specified]-Tg(KRT1-5-cre)5132Jlj Tg(KRT5-E2F1)2Dgj Brca1tm1Cxd/Brca1tm2Cxd  •  [not specified]-Tg(KRT5-cre)1Jlj Tg(KRT5-E2F1)2Dgj Brca1tm1Cxd/Brca1tm2Cxd  •  [not specified]-Tg(KRT5-cre)1Jlj Tg(KRT5-E2F1)2Dgj Brca1tm1Cxd/tm2Cxd  •  [not specified]-Tg(KRT5-cre)5132Jlj Tg(KRT5-E2F1)2Dgj Brca1tm1Cxd/Brca1tm2Cxd

Description

Compound mutant mice. The genetic background of these mice contained contributions from 129S6/SvEvTac, Black Swiss, C57BL/6J, SJL/J, and possibly SSIN, C3H, and/or other strains.

Strain Genetics

Tg(KRT5-E2F1)2Dgj
Brca1tm1Cxd / Brca1tm2Cxd
Tg(KRT5-cre)5132Jlj

Models

6 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Ear tumor Ear

0

References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26

Mouth squamous cell carcinoma Mouth

20

References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26

Mouth tumor Mouth

20

References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26

Skin squamous cell carcinoma Skin

100

References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26

Uterus - Cervix tumor Uterus - Cervix

0

References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26

Vagina tumor Vagina

0

References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26