Strain Summary[not specified]-Brca1^tm1Cxd/Brca1^tm2Cxd Tg(KRT5-E2F1)2Dgj

Strain Name	[not specified]-Brca1^tm1Cxd/Brca1^tm2Cxd Tg(KRT5-E2F1)2Dgj
Strain Type(s)	targeted mutation (conditional) • targeted mutation (knockout) • transgenic
Strain Synonym(s)	K5 E2F1.1:Brca1^co/- • K5 E2F1:Brca1^co/- • [not specified]-Tg(KRT5-E2F1)2Dgj Brca1^tm1Cxd/Brca1^tm2Cxd • [not specified]-Tg(KRT5-E2F1)2Dgj Brca1^{tm1Cxd/tm2Cxd}
Description	Compound mutant mice. The genetic background of these mice contained contributions from 129S6/SvEvTac, Black Swiss, C57BL/6J, SJL/J, and possibly SSIN, C3H, and/or other strains.
Strain Genetics	List all models in MMHCdb carrying the Tg(KRT5-E2F1)2Dgj allele Tg(KRT5-E2F1)2Dgj
	List all models in MMHCdb carrying the Brca1^tm1Cxd allele List all models in MMHCdb carrying the Brca1^tm2Cxd allele Brca1^tm1Cxd / Brca1^tm2Cxd

Models
9 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Ear tumor - epithelial	Ear				observed		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Mouth tumor - epithelial	Mouth				observed		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Skin squamous cell carcinoma	Skin			observed	observed		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Uterus - Cervix papilloma	Uterus - Cervix		observed				References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Uterus - Cervix squamous cell carcinoma	Uterus - Cervix		observed				References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Vagina squamous cell carcinoma	Vagina		observed				References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Vagina tumor - epithelial	Vagina		observed				References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
(Unspecified organ) tumor	(Unspecified organ)				94.74		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
(Unspecified organ) tumor - epithelial	(Unspecified organ)				94.74		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26

Models