Strain Summary[not specified]-Brca1tm2Cxd/+ Tg(KRT5-E2F1)2Dgj
Strain Name |
[not specified]-Brca1tm2Cxd/+ Tg(KRT5-E2F1)2Dgj |
Strain Type(s) |
targeted mutation (conditional) • transgenic |
Strain Synonym(s) |
K5 E2F1.1:Brca1co/+ • K5 E2F1:Brca1co/+ • [not specified]-Tg(KRT5-E2F1)2Dgj Brca1tm2Cxd/+ |
Description |
Compound mutant mice. The genetic background of these mice contained contributions from 129S6/SvEvTac, Black Swiss, C57BL/6J, SJL/J, and possibly SSIN, C3H, and/or other strains. |
Strain Genetics |
Brca1tm2Cxd / Brca1+ |
| Tg(KRT5-E2F1)2Dgj |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Ear tumor - epithelial | Ear |
0 |
References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26 |
|||||
| Mouth tumor - epithelial | Mouth |
16.67 |
References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26 |
|||||
| Skin tumor - epithelial | Skin |
observed |
References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26 |
|||||
| Uterus - Cervix tumor - epithelial | Uterus - Cervix |
observed |
References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26 |
|||||
| Vagina tumor - epithelial | Vagina |
observed |
References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26 |
|||||
| (Unspecified organ) tumor | (Unspecified organ) |
50 |
References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26 |
|||||