Strain Summary[not specified]-Brca1tm2Cxd/+ Tg(KRT5-E2F1)2Dgj

Strain Name

[not specified]-Brca1tm2Cxd/+ Tg(KRT5-E2F1)2Dgj

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

K5 E2F1.1:Brca1co/+  •  K5 E2F1:Brca1co/+  •  [not specified]-Tg(KRT5-E2F1)2Dgj Brca1tm2Cxd/+

Description

Compound mutant mice. The genetic background of these mice contained contributions from 129S6/SvEvTac, Black Swiss, C57BL/6J, SJL/J, and possibly SSIN, C3H, and/or other strains.

Strain Genetics

Brca1tm2Cxd / Brca1+
Tg(KRT5-E2F1)2Dgj

Models

6 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Ear tumor - epithelial Ear

0

References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26

Mouth tumor - epithelial Mouth

16.67

References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26

Skin tumor - epithelial Skin

observed

References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26

Uterus - Cervix tumor - epithelial Uterus - Cervix

observed

References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26

Vagina tumor - epithelial Vagina

observed

References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26

(Unspecified organ) tumor (Unspecified organ)

50

References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26