Strain SummaryCE129F2-Trp53tm1Tyj
Strain Name |
CE129F2-Trp53tm1Tyj |
Strain Type(s) |
hybrid • targeted mutation (knockout) |
Strain Synonym(s) |
CE:129 F2 mice null for Trp53 • CE/129-Trp53-/- F2 • CE/J:129-Trp53-/- F2 • CE/J:129-Trp53tm1Tyj • F2 CE:129-Trp53-/- • F2 CE/129 P53 -/- • Trp53 null |
Description |
Homozygous mice. These mice were generated by crossing CE129F1-Trp53tm1Tyj/+ heterozygous mice (CE/J background female x 129 background male). |
Strain Genetics |
Trp53tm1Tyj / Trp53tm1Tyj |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Blood vessel hemangioma | Blood vessel |
1.9 |
References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75 |
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| Blood vessel hemangiosarcoma | Blood vessel |
22 |
References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75 |
|||||
| Connective tissue - Fibroblast fibrosarcoma | Connective tissue - Fibroblast |
7.4 |
References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75 |
|||||
| Leukocyte lymphoma | Leukocyte |
63 |
References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75 |
|||||
| Leukocyte lymphoma | Thymus |
52 |
References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75 |
|||||
| Mesodermal cell/mesoblast sarcoma | Mesodermal cell/mesoblast |
31 |
References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75 |
|||||
| Muscle - Striated - Skeletal rhabdomyosarcoma | Muscle - Striated - Skeletal |
1.9 |
References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75 |
|||||
| Ovary hyperplasia | Ovary |
3.7 |
References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75 |
|||||
| (Unspecified organ) tumor | (Unspecified organ) |
98 |
References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75 |
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