Strain SummaryCE129F2-Trp53tm1Tyj/+

Strain Name

 CE129F2-Trp53tm1Tyj/+

Strain Type(s)

 hybrid  •  targeted mutation (knockout)

Strain Synonym(s)

 CE:129 F2 mice heterozygous for Trp53  •  CE:129-Trp53+/-  •  CE/129-Trp53+/- F2  •  CE/J:129-Trp53+/- F2  •  CE/J:129-Trp53tm1Tyj  •  CE/J:129-Trp53tm1Tyj-Trp53+/-  •  F2 CE/129 Trp53+/-  •  F2 CE:129-Trp53+/-  •  F2 CE/129 P53 +/-  •  F2 Trp53+/-  •  F2 Trp53 heterozygous mice

Description

 Heterozygous mice. These mice were generated by crossing CE129F1-Trp53tm1Tyj/+ heterozygous mice (CE/J background female x 129 background male).

Strain Genetics

 Trp53tm1Tyj / Trp53+

Models

23 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Blood vessel hemangioma Blood vessel

4.2

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Blood vessel hemangiosarcoma Blood vessel

7.0

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Bone osteosarcoma Bone

11

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Sites of Metastasis: (Unspecified organ)
Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast

7.0

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell

1.4

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Leukocyte - Myelocyte (Granulocyte) leukemia Leukocyte - Myelocyte (Granulocyte)

1.4

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Leukocyte lymphoma Leukocyte

14

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Liver hepatoma Liver

13

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Lung carcinoma Lung

1.4

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Sites of Metastasis: (Unspecified organ)
Mammary gland carcinoma Mammary gland

1.4

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

32

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Muscle - Smooth leiomyosarcoma Muscle - Smooth

1.4

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal

2.8

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Ovary carcinoma Ovary

1.4

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Ovary hyperplasia Ovary

7.0

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Preputial gland (male) hyperplasia Preputial gland (male)

observed

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Sertoli cell (sex not specified) tumor Sertoli cell (sex not specified)

1.4

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Sites of Metastasis: (Unspecified organ)
Uterus - Endometrium hyperplasia Uterus - Endometrium

31

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

(Unspecified organ) adenocarcinoma - cystic (Unspecified organ)

1.4

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

(Unspecified organ) adenoma (Unspecified organ)

9.9

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

(Unspecified organ) cyst (Unspecified organ)

8.5

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

(Unspecified organ) squamous cell carcinoma (Unspecified organ)

1.4

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

(Unspecified organ) tumor (Unspecified organ)

100

References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75