Strain Summary(129S4.129S2 x C57BL/6J)F1-Nf1^tm1Tyj Trp53^tm1Tyj/+ +

Strain Name	(129S4.129S2 x C57BL/6J)F1-Nf1^tm1Tyj Trp53^tm1Tyj/+ +
Strain Type(s)	hybrid • targeted mutation (knockout)
Strain Synonym(s)	(129S4.129S2 x C57BL/6J)F1-Nf1^tm1Tyj/+ Trp53^tm1Tyj/+ • NPcis-129XB6 F₁ cross B
Description	129S4.129S2-Nf1^tm1Tyj Trp53^tm1Tyj/+ + "cis" (mutations both carried on the same copy of chromosome 11) female mice were bred to male C57BL/6J mice.
Strain Genetics	List all models in MMHCdb carrying the Nf1^tm1Tyj allele Nf1^tm1Tyj / Nf1⁺
	List all models in MMHCdb carrying the Trp53^tm1Tyj allele Trp53^tm1Tyj / Trp53⁺

Models
1 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
CNS - Brain - Astrocyte astrocytoma	CNS - Brain - Astrocyte				73		References: Reilly KM, Proc Natl Acad Sci U S A 2004 Aug 31;101(35):13008-13 1 pathology image(s)

Models