Strain SummaryFVB-Itgb1tm1Mll Gt(ROSA)26Sortm1Sor Tg(MMTV-cre)7Mul Tg(MMTV-PyVT)634Mul
Strain Name |
FVB-Itgb1tm1Mll Gt(ROSA)26Sortm1Sor Tg(MMTV-cre)7Mul Tg(MMTV-PyVT)634Mul |
Strain Type(s) |
targeted mutation (conditional) • targeted mutation (knock-in) • transgenic |
Strain Synonym(s) |
B1LoxP1 MMTC/Cre/PyV MT GTRosa26 |
Description |
The background of these mice was FVB. Mice carried the Tg(MMTV-cre)7Mul, Tg(MMTV-PyVT)634Mul, and Gt(ROSA)26Sortm1Sor transgenes and were heterozygous for Itgb1tm1Mll. |
Strain Genetics |
Tg(MMTV-cre)7Mul |
| Gt(ROSA)26Sortm1Sor | |
| Itgb1tm1Mll / Itgb1tm1Mll | |
| Tg(MMTV-PyVT)634Mul |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Mammary gland hyperplasia | Mammary gland |
observed |
References: White DE, Cancer Cell 2004 Aug;6(2):159-70 |
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| Mammary gland tumor | Mammary gland |
observed |
References: White DE, Cancer Cell 2004 Aug;6(2):159-70 |
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