Strain SummaryFVB-Itgb1tm1Mll Gt(ROSA)26Sortm1Sor Tg(MMTV-cre)7Mul Tg(MMTV-PyVT)634Mul

Strain Name

FVB-Itgb1tm1Mll Gt(ROSA)26Sortm1Sor Tg(MMTV-cre)7Mul Tg(MMTV-PyVT)634Mul

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knock-in)  •  transgenic

Strain Synonym(s)

B1LoxP1 MMTC/Cre/PyV MT GTRosa26

Description

The background of these mice was FVB. Mice carried the Tg(MMTV-cre)7Mul, Tg(MMTV-PyVT)634Mul, and Gt(ROSA)26Sortm1Sor transgenes and were heterozygous for Itgb1tm1Mll.

Strain Genetics

Tg(MMTV-cre)7Mul
Gt(ROSA)26Sortm1Sor
Itgb1tm1Mll / Itgb1tm1Mll
Tg(MMTV-PyVT)634Mul

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Mammary gland hyperplasia Mammary gland

observed

References: White DE, Cancer Cell 2004 Aug;6(2):159-70

Mammary gland tumor Mammary gland

observed

References: White DE, Cancer Cell 2004 Aug;6(2):159-70