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Strain SummaryB6;129-Trp53^tm1Wahl

Strain Name	B6;129-Trp53^tm1Wahl
Strain Type(s)	targeted mutation (knock-in)
Strain Synonym(s)	p53^QSval/QSval • Trp53^QSval/QSval • p53QSval/QSval
Description	Homozygous mice. The genetic background of these mice was stated to be on a ">=75%" C57BL/6 genetic background. This background also contained some 129S4/SvJae and possibly some other strain or strains.
Strain Genetics	List all models in MMHCdb carrying the Trp53^tm1Wahl allele Trp53^tm1Wahl / Trp53^tm1Wahl

Models
16 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Bone osteosarcoma	Bone				0		References: Nister M, Oncogene 2005 May 19;24(22):3563-73
CNS - Brain glioma - malignant	CNS - Brain				1.3		References: Nister M, Oncogene 2005 May 19;24(22):3563-73
CNS - Spinal cord glioma - malignant	CNS - Spinal cord				1.3		References: Nister M, Oncogene 2005 May 19;24(22):3563-73
Cheek tumor - anaplastic	Cheek				1.3		References: Nister M, Oncogene 2005 May 19;24(22):3563-73
Connective tissue - Fibroblast fibrosarcoma	Connective tissue - Fibroblast				5.3		References: Nister M, Oncogene 2005 May 19;24(22):3563-73
Gonad (sex not specified) tumor	Gonad (sex not specified)				1.3		References: Nister M, Oncogene 2005 May 19;24(22):3563-73
Leukocyte lymphoma	Leukocyte				25 - 62		References: Nister M, Oncogene 2005 May 19;24(22):3563-73
Leukocyte lymphoma	Thymus				37		References: Nister M, Oncogene 2005 May 19;24(22):3563-73
Mesodermal cell/mesoblast sarcoma	Mesodermal cell/mesoblast				20		References: Nister M, Oncogene 2005 May 19;24(22):3563-73
Mesodermal cell/mesoblast sarcoma - poorly differentiated	Mesodermal cell/mesoblast				observed		References: Nister M, Oncogene 2005 May 19;24(22):3563-73
Mesodermal cell/mesoblast sarcoma - well differentiated	Mesodermal cell/mesoblast				observed		References: Nister M, Oncogene 2005 May 19;24(22):3563-73
Testis tumor - malignant	Testis				1.3		References: Nister M, Oncogene 2005 May 19;24(22):3563-73
(Unspecified organ) angiosarcoma	(Unspecified organ)				9.2		References: Nister M, Oncogene 2005 May 19;24(22):3563-73
(Unspecified organ) carcinoma	(Unspecified organ)				0		References: Nister M, Oncogene 2005 May 19;24(22):3563-73
(Unspecified organ) histiocytoma - fibrous - malignant	(Unspecified organ)				observed		References: Nister M, Oncogene 2005 May 19;24(22):3563-73
(Unspecified organ) tumor	(Unspecified organ)				88 - 100		References: Nister M, Oncogene 2005 May 19;24(22):3563-73