Strain SummarySTOCK Tg(LPV-TAg121)2Tvd Trp53tm1Brd/+
Strain Name |
STOCK Tg(LPV-TAg121)2Tvd Trp53tm1Brd/+ |
Strain Type(s) |
targeted mutation (knockout) • transgenic |
Strain Synonym(s) |
TgT121 p53+/- • p53+/-T121 • T121p53+/- |
Description |
These mice carry the transgene and are heterozygous for the targeted allele. The genetic background of these mice was a mixture of at least C57BL/6, DBA/2, and 129S7/SvEvBrd-Hprt+. Other strains may also have been involved. |
Strain Genetics |
Trp53tm1Brd / Trp53+ |
| Tg(LPV-TAg121)2Tvd |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| CNS - Brain - Choroid plexus dysplasia | CNS - Brain - Choroid plexus |
observed |
References: Nister M, Oncogene 2005 May 19;24(22):3563-73 |
|||||
| CNS - Brain - Choroid plexus tumor | CNS - Brain - Choroid plexus |
100 |
References: Nister M, Oncogene 2005 May 19;24(22):3563-73 |
|||||