Strain SummaryB6.129-Bmal1tm1Bra/+

Strain Name

 B6.129-Bmal1tm1Bra/+

Strain Type(s)

 congenic  •  targeted mutation (knockout)

Strain Synonym(s)

 B6.129-Arntltm1Bra/+  •  Bmal1+/-

Description

 Heterozygous mice. These mice have been backcrossed to C57BL/6. The mutation was generated in a "129/Sv" (substrain not specified) genetic background.

Strain Genetics

 Bmal1tm1Bra / Bmal1+

Models

14 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Bone osteosarcoma Bone

0

References: Lee S, PLoS One 2010;5(6):e10995

Bone osteosarcoma Bone gamma-radiation

0

References: Lee S, PLoS One 2010;5(6):e10995

Leukocyte lymphoma Leukocyte

12.9

References: Lee S, PLoS One 2010;5(6):e10995

Leukocyte lymphoma Leukocyte gamma-radiation

33.33

References: Lee S, PLoS One 2010;5(6):e10995

Leukocyte lymphoma Leukocyte gamma-radiation   ⋅   jet-lag light cycle

observed

References: Lee S, PLoS One 2010;5(6):e10995

Sites of Metastasis: Salivary gland
Liver hepatocellular carcinoma Liver gamma-radiation   ⋅   jet-lag light cycle

observed

References: Lee S, PLoS One 2010;5(6):e10995

Liver hepatocellular tumor Liver

3.23

References: Lee S, PLoS One 2010;5(6):e10995

Liver hepatocellular tumor Liver gamma-radiation

7.41

References: Lee S, PLoS One 2010;5(6):e10995

Ovary - Granulosa cell tumor Ovary - Granulosa cell

3.23

References: Lee S, PLoS One 2010;5(6):e10995

Ovary - Granulosa cell tumor Ovary - Granulosa cell gamma-radiation

3.7

References: Lee S, PLoS One 2010;5(6):e10995

Reproductive system (sex not specified) hyperplasia - cystic Reproductive system (sex not specified)

12.9

References: Lee S, PLoS One 2010;5(6):e10995

Reproductive system (sex not specified) hyperplasia - cystic Reproductive system (sex not specified) gamma-radiation

14.81

References: Lee S, PLoS One 2010;5(6):e10995

(Unspecified organ) angiosarcoma (Unspecified organ)

0

References: Lee S, PLoS One 2010;5(6):e10995

(Unspecified organ) angiosarcoma (Unspecified organ) gamma-radiation

0

References: Lee S, PLoS One 2010;5(6):e10995