Strain SummaryC57BL/6-Cry1tm1Asn Cry2tm1Asn
Strain Name |
C57BL/6-Cry1tm1Asn Cry2tm1Asn |
Strain Type(s) |
targeted mutation (knockout) |
Strain Synonym(s) |
Cry1-/-;Cry2-/- |
Description |
Double homozygous mice. These mice are the product of an intercross between strains on a congenic C57BL/6 background. The mutations were each generated on a 129P2/OlaHsd genetic background. |
Strain Genetics |
Cry1tm1Asn / Cry1tm1Asn |
| Cry2tm1Asn / Cry2tm1Asn |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Bone osteosarcoma | Bone |
0 |
References: Lee S, PLoS One 2010;5(6):e10995 |
|||||
| Bone osteosarcoma | Bone | gamma-radiation |
3.33 |
References: Lee S, PLoS One 2010;5(6):e10995 |
||||
| Bone osteosarcoma | Bone | gamma-radiation ⋅ jet-lag light cycle |
6.06 |
References: Lee S, PLoS One 2010;5(6):e10995 |
||||
| Intestine tumor | Intestine | gamma-radiation ⋅ jet-lag light cycle |
observed |
References: Lee S, PLoS One 2010;5(6):e10995 |
||||
| Kidney tumor | Kidney | gamma-radiation ⋅ jet-lag light cycle |
observed |
References: Lee S, PLoS One 2010;5(6):e10995 |
||||
| Leukocyte lymphoma | Leukocyte |
13.33 |
References: Lee S, PLoS One 2010;5(6):e10995 Sites of Metastasis: Liver 1 pathology image(s) |
|||||
| Leukocyte lymphoma | Leukocyte | gamma-radiation |
23.33 |
References: Lee S, PLoS One 2010;5(6):e10995 |
||||
| Leukocyte lymphoma | Leukocyte | gamma-radiation ⋅ jet-lag light cycle |
36.36 |
References: Lee S, PLoS One 2010;5(6):e10995 Sites of Metastasis: Salivary gland |
||||
| Liver hepatocellular carcinoma | Liver |
observed |
References: Lee S, PLoS One 2010;5(6):e10995 1 pathology image(s) |
|||||
| Liver hepatocellular carcinoma | Liver | gamma-radiation ⋅ jet-lag light cycle |
observed |
References: Lee S, PLoS One 2010;5(6):e10995 |
||||
| Liver hepatocellular tumor | Liver |
6.67 |
References: Lee S, PLoS One 2010;5(6):e10995 |
|||||
| Liver hepatocellular tumor | Liver | gamma-radiation |
13.33 |
References: Lee S, PLoS One 2010;5(6):e10995 |
||||
| Liver hepatocellular tumor | Liver | gamma-radiation ⋅ jet-lag light cycle |
18.18 |
References: Lee S, PLoS One 2010;5(6):e10995 |
||||
| Ovary - Granulosa cell tumor | Ovary - Granulosa cell |
3.33 |
References: Lee S, PLoS One 2010;5(6):e10995 1 pathology image(s) |
|||||
| Ovary - Granulosa cell tumor | Ovary - Granulosa cell | gamma-radiation |
6.67 |
References: Lee S, PLoS One 2010;5(6):e10995 |
||||
| Ovary - Granulosa cell tumor | Ovary - Granulosa cell | gamma-radiation ⋅ jet-lag light cycle |
9.09 |
References: Lee S, PLoS One 2010;5(6):e10995 1 pathology image(s) |
||||
| Pancreas tumor | Pancreas | gamma-radiation ⋅ jet-lag light cycle |
observed |
References: Lee S, PLoS One 2010;5(6):e10995 |
||||
| Reproductive system (sex not specified) hyperplasia - cystic | Reproductive system (sex not specified) |
20 |
References: Lee S, PLoS One 2010;5(6):e10995 |
|||||
| Reproductive system (sex not specified) hyperplasia - cystic | Reproductive system (sex not specified) | gamma-radiation |
20 |
References: Lee S, PLoS One 2010;5(6):e10995 |
||||
| Reproductive system (sex not specified) hyperplasia - cystic | Reproductive system (sex not specified) | gamma-radiation ⋅ jet-lag light cycle |
30.3 |
References: Lee S, PLoS One 2010;5(6):e10995 |
||||
| Seminal vesicle hyperplasia - cystic | Seminal vesicle | gamma-radiation ⋅ jet-lag light cycle |
observed |
References: Lee S, PLoS One 2010;5(6):e10995 1 pathology image(s) |
||||
| Uterus hyperplasia - cystic | Uterus |
observed |
References: Lee S, PLoS One 2010;5(6):e10995 1 pathology image(s) |
|||||
| Uterus hyperplasia - cystic | Uterus | gamma-radiation ⋅ jet-lag light cycle |
observed |
References: Lee S, PLoS One 2010;5(6):e10995 |
||||
| (Unspecified organ) angiosarcoma | (Unspecified organ) |
0 |
References: Lee S, PLoS One 2010;5(6):e10995 |
|||||
| (Unspecified organ) angiosarcoma | (Unspecified organ) | gamma-radiation |
0 |
References: Lee S, PLoS One 2010;5(6):e10995 |
||||
| (Unspecified organ) angiosarcoma | (Unspecified organ) | gamma-radiation ⋅ jet-lag light cycle |
3.03 |
References: Lee S, PLoS One 2010;5(6):e10995 |
||||