Strain SummaryC57BL/6-Per1tm1Brd Per2tm1Brd

Strain Name

C57BL/6-Per1tm1Brd Per2tm1Brd

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

Per1-/-;Per2m/m

Description

Double homozygous mice. These mice are the product of an intercross between strains on a congenic C57BL/6 background. The mutations were each generated on a 129S7/SvEvBrd-Hprt+ genetic background.

Strain Genetics

Per1tm1Brd / Per1tm1Brd
Per2tm1Brd / Per2tm1Brd

Models

26 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Bone osteosarcoma Bone

0

References: Lee S, PLoS One 2010;5(6):e10995

Bone osteosarcoma Bone gamma-radiation

2.13

References: Lee S, PLoS One 2010;5(6):e10995

Bone osteosarcoma Bone gamma-radiation   ⋅   jet-lag light cycle

4.08

References: Lee S, PLoS One 2010;5(6):e10995

Intestine tumor Intestine gamma-radiation   ⋅   jet-lag light cycle

observed

References: Lee S, PLoS One 2010;5(6):e10995

Kidney tumor Kidney gamma-radiation   ⋅   jet-lag light cycle

observed

References: Lee S, PLoS One 2010;5(6):e10995

Leukocyte lymphoma Leukocyte

17.5

References: Lee S, PLoS One 2010;5(6):e10995

Sites of Metastasis: Liver

1 pathology image(s)

Leukocyte lymphoma Leukocyte gamma-radiation

36.17

References: Lee S, PLoS One 2010;5(6):e10995

Leukocyte lymphoma Leukocyte gamma-radiation   ⋅   jet-lag light cycle

38.78

References: Lee S, PLoS One 2010;5(6):e10995

Sites of Metastasis: Salivary gland

Liver hepatocellular carcinoma Liver

observed

References: Lee S, PLoS One 2010;5(6):e10995

1 pathology image(s)

Liver hepatocellular carcinoma Liver gamma-radiation   ⋅   jet-lag light cycle

observed

References: Lee S, PLoS One 2010;5(6):e10995

Liver hepatocellular tumor Liver

10

References: Lee S, PLoS One 2010;5(6):e10995

Liver hepatocellular tumor Liver gamma-radiation

17.02

References: Lee S, PLoS One 2010;5(6):e10995

Liver hepatocellular tumor Liver gamma-radiation   ⋅   jet-lag light cycle

24.49

References: Lee S, PLoS One 2010;5(6):e10995

Ovary - Granulosa cell tumor Ovary - Granulosa cell

2.5

References: Lee S, PLoS One 2010;5(6):e10995

1 pathology image(s)

Ovary - Granulosa cell tumor Ovary - Granulosa cell gamma-radiation

6.38

References: Lee S, PLoS One 2010;5(6):e10995

Ovary - Granulosa cell tumor Ovary - Granulosa cell gamma-radiation   ⋅   jet-lag light cycle

10.2

References: Lee S, PLoS One 2010;5(6):e10995

1 pathology image(s)

Pancreas tumor Pancreas gamma-radiation   ⋅   jet-lag light cycle

observed

References: Lee S, PLoS One 2010;5(6):e10995

Reproductive system (sex not specified) hyperplasia - cystic Reproductive system (sex not specified)

10

References: Lee S, PLoS One 2010;5(6):e10995

Reproductive system (sex not specified) hyperplasia - cystic Reproductive system (sex not specified) gamma-radiation

17.02

References: Lee S, PLoS One 2010;5(6):e10995

Reproductive system (sex not specified) hyperplasia - cystic Reproductive system (sex not specified) gamma-radiation   ⋅   jet-lag light cycle

28.57

References: Lee S, PLoS One 2010;5(6):e10995

Seminal vesicle hyperplasia - cystic Seminal vesicle gamma-radiation   ⋅   jet-lag light cycle

observed

References: Lee S, PLoS One 2010;5(6):e10995

1 pathology image(s)

Uterus hyperplasia - cystic Uterus

observed

References: Lee S, PLoS One 2010;5(6):e10995

1 pathology image(s)

Uterus hyperplasia - cystic Uterus gamma-radiation   ⋅   jet-lag light cycle

observed

References: Lee S, PLoS One 2010;5(6):e10995

(Unspecified organ) angiosarcoma (Unspecified organ)

0

References: Lee S, PLoS One 2010;5(6):e10995

(Unspecified organ) angiosarcoma (Unspecified organ) gamma-radiation

0

References: Lee S, PLoS One 2010;5(6):e10995

(Unspecified organ) angiosarcoma (Unspecified organ) gamma-radiation   ⋅   jet-lag light cycle

0

References: Lee S, PLoS One 2010;5(6):e10995