Strain SummaryB6.129-ApcMin/+ Prkcatm1Far

Strain Name

B6.129-ApcMin/+ Prkcatm1Far

Strain Type(s)

chemically induced mutation  •  congenic  •  targeted mutation (knockout)

Strain Synonym(s)

B6(N4) ApcMin/+PKCAlpha-/-

Description

Mice on a mixed 129S2/Sv and C57BL/6J background were backcrossed 4 times to C57BL/6J. Mice were heterozygous for ApcMin and homozygous for Prkcatm1Far.

Strain Genetics

ApcMin / Apc+
Prkcatm1Far / Prkcatm1Far

Models

5 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon

observed

References: Oster H, Cancer Res 2006 Jul 15;66(14):6955-63

Intestine - Small Intestine - Distal tumor Intestine - Small Intestine - Distal

observed

References: Oster H, Cancer Res 2006 Jul 15;66(14):6955-63

Intestine - Small Intestine - Medial tumor Intestine - Small Intestine - Medial

observed

References: Oster H, Cancer Res 2006 Jul 15;66(14):6955-63

Intestine - Small Intestine - Proximal tumor Intestine - Small Intestine - Proximal

observed

References: Oster H, Cancer Res 2006 Jul 15;66(14):6955-63

Intestine - Small Intestine tumor Intestine - Small Intestine

observed

References: Oster H, Cancer Res 2006 Jul 15;66(14):6955-63