Strain Summary129S2/Sv-Prkca^tm1Far

Strain Name	129S2/Sv-Prkca^tm1Far
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	PKCalpha^-/-
Description	Homozygous mice on a 129S2/Sv background with some contribution from 129P2/PlaHsd.
Strain Genetics	List all models in MMHCdb carrying the Prkca^tm1Far allele Prkca^tm1Far / Prkca^tm1Far

Models
7 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Large Intestine - Colon polyp	Intestine - Large Intestine - Colon					observed	References: Oster H, Cancer Res 2006 Jul 15;66(14):6955-63
Intestine - Small Intestine - Distal polyp	Intestine - Small Intestine - Distal					observed	References: Oster H, Cancer Res 2006 Jul 15;66(14):6955-63
Intestine - Small Intestine - Medial polyp	Intestine - Small Intestine - Medial					observed	References: Oster H, Cancer Res 2006 Jul 15;66(14):6955-63
Intestine - Small Intestine - Proximal polyp	Intestine - Small Intestine - Proximal					observed	References: Oster H, Cancer Res 2006 Jul 15;66(14):6955-63
Intestine adenoma	Intestine					observed	References: Oster H, Cancer Res 2006 Jul 15;66(14):6955-63
Intestine carcinoma	Intestine					observed	References: Oster H, Cancer Res 2006 Jul 15;66(14):6955-63
Intestine polyp	Intestine					observed	References: Oster H, Cancer Res 2006 Jul 15;66(14):6955-63

Models