Strain Summary[not specified]-Tg(WAPT121)66Tvd Trp53tm1Tyj/+

Strain Name

[not specified]-Tg(WAPT121)66Tvd Trp53tm1Tyj/+

Strain Type(s)

targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

WAP-T121+ p53+/-

Description

Compound mutant mice. The genetic background of these mice was not specified but included at least some C57BL/6J, DBA/2J, and 129S2/SvPas.

Strain Genetics

Tg(WAPT121)66Tvd
Trp53tm1Tyj / Trp53+

Models

8 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Leukocyte lymphoma Thymus

observed

References: Simin K, PLoS Biol 2004 Feb;2(2):E22

Mammary gland adenocarcinoma Mammary gland

very high

References: Simin K, PLoS Biol 2004 Feb;2(2):E22

Mammary gland adenocarcinoma - glandular Mammary gland

29

References: Simin K, PLoS Biol 2004 Feb;2(2):E22

1 pathology image(s)

Mammary gland adenocarcinoma - solid Mammary gland

94

References: Simin K, PLoS Biol 2004 Feb;2(2):E22

1 pathology image(s)

Mammary gland carcinoma - spindle cell Mammary gland

0

References: Simin K, PLoS Biol 2004 Feb;2(2):E22

Mammary gland tumor Mammary gland

89 - 100

References: Simin K, PLoS Biol 2004 Feb;2(2):E22

33 cytogenetic image(s)

Mammary gland tumor - pilar Mammary gland

0

References: Simin K, PLoS Biol 2004 Feb;2(2):E22

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

observed

References: Simin K, PLoS Biol 2004 Feb;2(2):E22